Pharma Science Monitor an International Journal of Pharmaceutical Sciences Ion Exchange Resin as an Imposing Method for Taste Masking: a Review
نویسندگان
چکیده
ION EXCHANGE RESIN AS AN IMPOSING METHOD FOR TASTE MASKING: A REVIEW A. M. Suthar* and M. M. Patel Saraswati School of Pharmacy, Ranela, Gujarat, India Kalol Institute of Pharmacy, Kalol, Gujatat, India ABSTRACT Taste masking becomes a pre-requisite for bitter drugs to improve the patient compliance especially in the pediatric and geriatric population. Conventional taste masking techniques such as the use of sweeteners, amino acids and flavoring agents alone are often inadequate in masking the taste of highly bitter drugs. The field of taste masking of active pharmaceutical ingredients (API) has been continuously evolving with varied technologies and new excipients. This review highlights complete account of ion exchange resin and its application in taste masking of bitter drugs.
منابع مشابه
Pharma Science Monitor an International Journal of Pharmaceutical Sciences a Review: Chemical Penetration Enhancers
متن کامل
Ion-exchange, an Approach to Prepare an Oral Floating Drug Delivery System for Diclofenac
Using ion-exchange resins, a multiple-unit type of oral floating dosage system has been prepared to prolong gastric emptying time of dosage form. The system is composed of beads of drug-resin complex, which are loaded with bicarbonate ions and coated with a hydrophobic polymer. The system is so designed that when the beads reach the stomach, chloride ions are exchanged with bicarbonate and drug...
متن کاملIon-exchange, an Approach to Prepare an Oral Floating Drug Delivery System for Diclofenac
Using ion-exchange resins, a multiple-unit type of oral floating dosage system has been prepared to prolong gastric emptying time of dosage form. The system is composed of beads of drug-resin complex, which are loaded with bicarbonate ions and coated with a hydrophobic polymer. The system is so designed that when the beads reach the stomach, chloride ions are exchanged with bicarbonate and drug...
متن کاملFormulation and In vitro Evaluation of Sustained Release Dosage Form with Taste Masking of Metformin Hydrochloride
An attempt was made to sustain the release of metformin HCl as well as to mask the bitter taste by complexation technique using strong cation-exchange resins, indion 244 and indion 264. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, mode of mixing, ratio of drug:resin and temperature. The resinate was evaluated for micromeritic properties, tast...
متن کاملTaste Masking of Azithromycin By Micro Encapsulation
Undesirable taste is one of several important formulation problems that are encountered with certain drugs. The problem of bitter and obnoxious taste of is a challenge to the pharmacist in the present scenario. Several oral pharmaceuticals and bulking agents have unpleasant, bitter-tasting components. The desire of improved palatability in these products has prompted the development of numerous...
متن کامل